Ontario takes aim at painkiller abuse

Painkiller abuse

These are great questions! Opioid analgesics (a.k.a. prescription painkillers) are a family of substances that act on the central nervous system (CNS) to change the way the brain perceives and responds to painful stimuli. When these painkillers are used in a different way than they were prescribed (i.e., taking more at a time than indicated or for longer than originally prescribed) or for long ...

The Human Life Bill: personhood revisited, or Congress takes aim at Roe v. Wade.

Taking aim at targets.

population: the European Prospective Investigation into Cancer in Norfolk (EPIC-Norfolk) population study. Int J Epidemiol 2004; 33: 189–198 23. Yuyun MF, Khaw KT, Luben R et al. Microalbuminuria and stroke in a British population: the European Prospective Investigation into Cancer in Norfolk (EPIC-Norfolk) population study. J Intern Med 2004; 255: 247–256 24. Harwell TS, Nelson RG, Little RR e...

Taking aim at cholera

In 1854, John Snow’s work on cholera in London immortalised the power of mapping as a tool for disease prevention and control. Over 160 years later, a more ambitious effort to map cholera has been reported in The Lancet. Forgoing so-called shoe leather epidemiology in favour of big data, Justin Lessler and colleagues used 279 cholera datasets covering 2283 locations in 37 countries, and cluster...

Taking aim at Sox18

A small molecule called Sm4 can disrupt interactions involving a transcription factor called Sox18, while having little impact on other members of the SoxF family.